Investigating the impact of exercise on neural stem cells and cognition: uncovering molecular mechanisms and exercise mimetic drugs

Led by Sahand Farmand

This project focuses on identifying the molecular mechanisms by which exercise modulates adult hippocampal neurogenesis (AHN), and cognition in addition to uncovering anti-ageing/cognition-enhancing exercise mimetic drugs.

In order to do this, the samples from the responders (a group of participants who showed improvement in pattern separation task following a 12 week exercise trial) will be investigated using a wide range of techniques.

Later, connectivity mapping will be used for discovery and validation of exercise mimetic drugs. This project is led by PhD student Sahand Farmand.